Conclusion:ĭigit ratio measures might be associated with breast cancer risk and age at onset of breast cancer. We also observed associations between both right 2D : 4D and Δ r−l and age at menopause, with increasing digit ratio measures related to earlier mean age at menopause. Among breast cancer cases, both right 2D : 4D and Δ r−l were inversely associated with age at diagnosis. We found a direct association between left 2D : 4D and breast cancer risk, an inverse association between Δ r−l and risk of breast cancer, but no association between right 2D : 4D and breast cancer risk. Hazard ratios (HR) and 95% confidence intervals (CI) for a one standard deviation difference in 2D : 4D measures were obtained from Weibull survival models, and linear regression models were used to examine potential associations between 2D : 4D measures and age at menarche and menopause. Of the 9044 women with available data, we identified 573 incident breast cancer cases. We derived the ratio of the lengths of the index and ring fingers (2D : 4D), and right minus left 2D : 4D (Δ r−l) from digit lengths measured from photocopies of participants’ hands collected during a recent follow-up of the Melbourne Collaborative Cohort Study, a prospective study including 24 469 women. We aimed to assess whether 2D : 4D measures are associated with breast cancer risk.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |